Search on: PHOSPHOLIPASES, SPLA2 
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Descriptor English:   Phospholipases A2, Secretory 
Descriptor Spanish:   Fosfolipasas A2 Secretoras 
Descriptor Portuguese:   Fosfolipases A2 Secretórias 
Synonyms English:   Phospholipases A2, Secreted
SPLA2 Phospholipases
Secreted Phospholipases A2
Secretory Phospholipase A2
sPLA(2)
sPLA2s
Phospholipase A2, Secretory
Phospholipases, SPLA2
Secretory Phospholipases A2  
Tree Number:   D08.811.277.352.100.680.750.937.750
Definition English:   A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes. 
Indexing Annotation English:   /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52667 
Unique Identifier:   D054497 

Occurrence in VHL:
 

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